Bioengineering Seminar Schedule
Fall 2001
Friday, Aug 24, Room 210 Hallowell Building (Univ Park) & CG624 (HMC)
2:30-3:30 pm
Herbert H. Lipowsky
Department of Bioengineering, Penn State
Welcome to New Students and Overview of the New Department of Bioengineering
Thursday,Aug 30, Room 210 Hallowell Building (Univ Park) & CG623 (HMC)
2:30 - 3:30 pm
Craig Grimes, Ph.D
Deptartment of Electical Engineering
Penn State University
Wireless, Passive Sensors for Biomedical Monitoring Applications
Thursday, September 6, Room 210 Hallowell Building (Univ Park) & CG623 (HMC)
2:30 - 3:30 pm
Dr. Christopher A. Siedlecki
Assistant Professor of Surgery and Bioengineering
Milton S. Hershey Medical Center
Molecular Interactions with Model Biomaterial Surfaces: Blood Coagulation/Thrombosis
Abstract
Thrombosis and coagulation on synthetic biomaterials remain significant impediments to the successful use of blood-contacting medical devices. These events arise from an intricate interplay between biomaterials, biological molecules/cells and the surrounding biological environment. Our research is directed towards understanding the molecular mechanisms that are responsible for initiation of these processes. The research plan utilizes a series of surface-sensitive techniques in conjunction with model biomaterial substrates. Improved understanding of these processes will be important in determining relevant parameters for the successful design of new biomaterials specifically designed for long-term implantation in the complex blood environment.
Friday, September 14, Room 210 Hallowell Building (Univ Park) & CG623 (HMC)
12:00 Noon - 1:00 pm
Professor Joseph Sommer
Department of Mechanical Engineering
Penn State University
Dual Axis Cranial Accelerometry to Assess Postural Sway
Abstract
Measurement of postural sway during quiet standing is particularly useful to predict idiopathic falling for elderly and neurological patients, and to quantify alcohol impairment for police field sobriety testing. Unfortunately, traditional methods such as timed stance tests and force plate center-of-pressure (COP) measurements are respectively either subjective or expensive and not portable. To this end, a dual axis accelerometer was interfaced to a microprocessor to record cranial accelerations and compute stability indicators. Traditional sway descriptors as well as random walk mean-square-distance (MSD) analyses will be discussed.
Thursday, September 20, Room 210 Hallowell Building (Univ Park) & CG623 (HMC)
2:30 - 3:30 pm
Chris Keating
Assistant Professor of Chemistry
Department of Chemistry
Penn State University
DNA hybridization for nanowire assembly and biosensing
Thursday, September 27, Room 210 Hallowell Building (Univ Park) & CG623 (HMC)
2:30 - 3:30 pm
Chris Rahn
Associate Professor of Mechanical Engineering
Penn State University
Design, Dynamics, and Control of Continuum Manipulators
Thursday/Friday, October 4, Room 210 Hallowell Building (Univ Park) & CG623 (HMC)
12:00 Noon - 1:00 pm
Ronald M. Summers, MD, PhD
Department of Diagnostic Radiology
National Institutes of Health
Bethesda, MD
Introduction to Computer-Aided Diagnosis for CT Colonography
Abstract
The American Cancer Society estimates that 10% of new cancer cases and cancer deaths will be due to cancer of
the colon and rectum. Many of these cases can be prevented if the precursor to colon cancer, colonic polyps, are
detected early and removed. The current best technique for detection of colonic polyps is colonoscopy. CT colonography
(CTC) is a new method for detection of colonic polyps which is now undergoing evaluation at a number of research
hospitals. In contrast to colonoscopy, CTC is less invasive and does not require sedation.
The appropriate way to perform and interpret CTC studies is still in evolution. Preliminary studies from other
investigators suggest that optimal interpretation consists primarily of using the two-dimensional CT images supplemented
where needed with analysis of three-dimensional (3D) ("virtual colonoscopy") reconstructions. Other work
suggests that 3D views may increase detection when used either alone or in combination with 2D images. Because
a typical CTC study consists of many 2D CT sections (as many as 1200 images must be inspected per patient), it
can be time consuming to interpret CTC studies. There is also a need to improve the sensitivity of CTC for polyp
detection. Computer-assisted polyp detection could potentially improve efficiency of interpretation and increase
sensitivity. For these reasons, we have developed a computer-assisted detection algorithm and tested it in an established
phantom model for colonic polyps and in patients. In this presentation, I will provide an overview of CT colonography
and describe our results with computer-aided polyp detection that lay the groundwork for future research.
Friday, October 12, Room 210 Hallowell Building (Univ Park) & CG623 (HMC)
12:00 - 1:00 pm
Srinivas Tadagadapa
Associate Professor of Electrical Engineering
Penn State University
BioMEMS
Friday, October 19
12:00 - 1:00 pm
Fan Yuan
Department of Biomedical Engineering
Duke University
Drug Delivery to Tumors
Friday, November 25, Room 210 Hallowell Building (Univ Park) & CG623 (HMC)
12:00 - 1:00 pm
Professor H. J. Sommer III
Department of Mechanical Engineering
Penn State University
Dual Axis Cranial Accelerometry to Assess Postural Sway
Thursday, November 1, Room 210 Hallowell Building (Univ Park) & CG623 (HMC)
2:30 - 3:30 pm
Richard Cyr
Department of Biology
Penn State University
Biomechanics of the Plant Cytoskeleton
Thursday , November 8, Room 210 Hallowell Building (Univ Park) & CG623 (HMC)
2:30 - 3:30 pm
Bruce Wheeler
Professor of Electrical and Biomedical Engineering
University of Illinois Urbana-Champaign
Patterned Neuron Grown on Microsubstrates
Thursday, November15, Room 210 Hallowell Building (Univ Park) & CG623 (HMC)
2:30 - 3:30 pm
John Blebea
Associate Professor of Surgery
Milton S. Hershey Medical Center
Quantitation and Modulation of Angiogenesis in the Chick Embryo
Friday/Thursday Novenber 21-22
No Seminar due to Thanksgiving Holiday
Thursday, November 29, Room 210 Hallowell Building (Univ Park) & CG623 (HMC)
12:10 - 1:10 pm
Edward R. Damiano
Department of Mechanical & Industrial Engineering
University of Illinois at Urbana-Champaign
Toward A New Understanding of the Interface Between Blood and the Vascular Endothelium
Thursday, December 6, Room 210 Hallowell Building (Univ Park) & CG623 (HMC)
2:30 - 3:30
Student presentations
Michael Dancu
Bioengineering Department, Penn State University
Simultaneous Effects of Wall Shear Stress and Circumferential Strain on Endothelial Cell (EC)
Behavior: An in vitro System and EC Gene Expression
For additional information, contact Ms. Doretta Garvey, Dept of Bioengineering, Tel: 814.865.1407 or E-Mail: bioe@psu.edu