Margaret Slattery
Assistant Professor and Undergraduate Program Coordinator
206B Hallowell Building
University Park, PA 16802
Phone: 814-865-8092 / Fax:814-863-0490
E-mail: mjs436@psu.edu
Education
Ph.D. Bioengineering, The Pennsylvania State University, 2006
Research and Teaching Interests
Dr. Slattery is affiliated with the Artificial Heart and Cardiovascular Fluid Dynamics Laboratories in the Bioengineering department. She contributes to studies designed to better understand blood damage, in particular hemolysis, and thrombogenicity of cardiovascular devices. Other on-going projects work to develop more sensitive in vitro techniques for determining thrombogenicity of cardiovascular prosthetics and correlating clinical thrombosis markers for more accurate detection and prediction of thromboembolic events in patients.
In addition to research activities, Dr. Slattery is the Undergraduate Program Coordinator for Bioengineering. She teaches the First-Year Seminars in Bioengineering as well as Bio-thermodynamics and Transport Phenomena. She is very interested in development of new course materials to improve student learning and educational assessment. Outside of Bioengineering Dr. Slattery is active in promoting, supporting, and participating in Women in Engineering Programs. She is also a faculty adviser for the Society of Women Engineers student group.
Recent Publications
Liang S, Slattery MJ, Wagner D, Simon SI, Dong C. Hydrodynamic shear rate regulates melanoma leukocyte aggregation, melanoma adhesion to the endothelium, and subsequent extravasation. Ann Biomed Eng, 36(4):661-71, 2008.
Wang J, Slattery MJ, Hoskins MH, Kunz R, Dong C, Du Q. Monte Carlo Simulation of Heterotypic Aggregation in Nonlinear Shear Flow. Mathematical Biosciences and Engin, 3(4):683-696, 2006.
Dong C, Slattery MJ, Liang S, and Peng HH. Melanoma cell extravasation under flow conditions is modulated by leukocytes and endogenously produced interleukin-8. Molecular and Cellular Biomechanics, 2:145-159, 2005.
Liang S, Slattery MJ, and Dong C. Shear stress and shear rate differentially affect the multi-step process of leukocyte-facilitated melanoma adhesion. Exp Cell Res. 310(2):282-292, 2005.
Slattery MJ, Liang S, and Dong C. Distinct role of hydrodynamic shear in leukocyte-facilitated tumor cell extravasation. Am J Physio Cell Physio. 288(4):C831-839, 2005.
Dong C, Slattery MJ, and Liang S. Micromechanics of tumor cell adhesion and migration under dynamic flow conditions. Frontiers in Bioscience. 10:379-384, 2005.
Slattery MJ and Dong C. Neutrophils influence melanoma adhesion and migration under flow conditions. Intl J Cancer. 106:713-722, 2003.
Dong C, Slattery MJ, Rank BM, and Yun J. In vitro characterization and micromechanics of tumor cell chemotactic protrusion, locomotion and extravasation. Ann Biomed Engin 30: 344-355, 2002.
Buchko CJ, Slattery MJ, Kozloff KM, and Martin DC. Mechanical properties of biocompatible protein polymer thin films. J Materials Res. 15(1): 231-242, 2000.
McCoy DE, Slattery MJ, and Stanton BA. Nucleotides regulate NaCl transport in mIMCD-K2 cells via P2X and P2Y purinergic receptors. Am. J Physiol. 277(4 Pt.2):F552-559, 1999.
Green RB, Slattery MJ, Gianferrari E, Kizer NL, McCoy DE, and Stanton BA. Hyperosmolarity inhibits sodium absorption and chloride secretion in mIMCD-K2 cells. Am J Physiol. 2 71(6 Pt 2): F1248-F1254, 1996.