Undergraduate Courses
100S Bioengineering Seminar (1) First-year seminar to introduce the role of engineering in biomedical research and in instrument development for the medical device industry.
201 Analysis of Molecules and Cells
(3) An analytical study of molecular and cellular phenomena including functional and metabolic interactions. Prerequisite: BIOL 141 , CHEM 112 , MATH 141 , concurrent PHYS 212.
301 Analysis of Physiological Systems (3) Linear systems analysis applied to electrical networks and lumped parameter models of physiological control systems. Prerequisite: BIOL 141 , PHYS 212 , MATH 250 or MATH 251, concurrent BIOE 302.
302 Physiological Simulation Laboratory (1) Computer laboratory designed to illustrate applications of control systems theory to physiological systems. Prerequisite: or concurrent: BIOE 301.
303 Bio-continuum Mechanics (3) Mechanical properties of fluids and solids with applications to tissue mechanics and vascular system. Prerequisite: BIOL 141 , E MCH 210 , MATH 230, MATH 251.
313 Biothermodynamics (3) Chemical processes, including material and energy balances and phase equilibria, with emphasis on biological applications. Prerequisites: BIOL 141 , CHEM 112, MATH 230 , MATH 251.
401 Introduction to Bioengineering Research and Design (3) Challenges and constraints of bioengineering research and design. Emphasis on immunoresponse, tissue mechanics, biological transport phenomena, and biomaterials. Prerequisite: BIOE 201 , BIOE 303, Concurrent: BIOE 404.
402 Biomedical Instrumentation and Measurements (3) Biomedical measurements laboratory including measurement of bioptentials, experiments in medical imaging techniques, and use of cardiovascular and pulmonary system instrumentation. Prerequisite or concurrent: MATH 250 or MATH 251, BIOE 301 or EE210 or EE 305 or PHYS 402.
403 Biomedical Instrumentation Laboratory (1) Biomedical measurements laboratory, including measurement of biopotentials, experiments in medical imaging techniques, and use of cardiovascular and pulmonary system instrumentation. Prerequisite: BIOE 402.
404 Data Analysis and Experiment Design (1) Statistical measures of data, and selection of experiment sample size to meet criteria. Prerequisite: BIOE 302 Concurrent: BIOE 401.
406 Medical Imaging (3) Physical principles and clinical applications of medical imaging methods. Prerequisite: PHYS 212.
409 Biofluid Mechanics (3) The fundamental relations in fluid mechanics and their application to biofluids including steady/unsteady flows, diseased states, devices and biorheology. Prerequisites: MATH 230, MATH 251, BIOE 303.
410 Biomedical Applications of Microfluidics (3) Study of fluid mechanics at small length scales. Low Reynolds number flow, electrokinetic flow, bioseparations in microfluidic devices. Prerequisites: BIOE 303 or ME 320.
413 Bioengineering Transport Phenomena (3) An integrated study of the fundamentals of mass transport processes with emphasis on the analysis of physiological systems. Prerequisite: BIOE 303 , BIOE 313 or CHEM 450.
419 Artificial Organs and Prosthetic Devices (3) Analysis of function and consideration of design concerns for biomedical implants, including prosthetic joints, electrical stimulators, and cardiovascular pumps. Prerequisite: MATH 250 . Prerequisite or concurrent: BIOL 141 or BIOL 472.
423 Reaction Kinetics of Biological Systems (3) Chemical kinetics and reaction equilibria with applications to the analysis of physiological function and the design of synthetic organs. Prerequisite: BIOL 141 , BIOE 313 or CH E 210 . Prerequisite or concurrent: BIOE 413 or CH E 302 and CH E 413.
440 Clinical Correlations (1) Engineering analysis applied to common disease states and therapies. Prerequisite: BIOE 402.
443 Biomedical Materials (3) Describe properties of materials and composites and their in vivo interactions. Prerequisite: MATSE 201.
444 Surfaces and the Biological Response to Materials (3) Focus is on the special properties of surfaces as an important causative and mediating agent in the biological response to materials. Prerequisite: CHEM 111, CHEM 113.
450W Bioengineering Senior Design (3) Application of engineering and physiological principles to design of artificial organs and life supportive devices. Prerequisite: BIOE 440 , ENGL 202C , senior standing.
490 Colloquium (1) Technical presentations related to research and industry concerns, and by students doing senior projects. Prerequisite: or concurrent: BIOE 450W.
496 Independent Studies (1-18) Opportunity for advanced undergraduate students to study indepenently in consultation with a faculty advisor.
497 Special Topics (1-9) This designation is assigned to new or developing undergraduate courses covering specialized areas of interest in bioengineering and course offerings may be infrequent. Past offerings have focused on topics such as artifical organs, medical ultrasound imaging and biomedical instrumentation.
497G Tissue Engineering: Concepts, Calculations and Applications (3) Introduction to interdisciplinary tissue engineering concepts, associated biochemical and biomechanical engineering calculations, and cardiovascular, musculoskeletal and other tissue application examples.
GRADUATE COURSES
501 Bioengineering Transport Phenomena(3) Application of the equations of mass, energy, and momentum conservation to physiological phenomena and to the design of artificial organs.
502 Introduction to Bioelectric Phenomena (3) Electric phenomena in nerve and muscle membrane potentials, Hodgkin-Huxley equations, volume conductor problem, applications to electrocardiography, electroencephalography, plethysmography.
503 Fluid Mechanics of Bioengineering Systems (3) Cardiovascular system and blood flow, non-Newtonian fluid description, vessel flows, unsteady flows and wave motion, windkessel theory, transmission line theory.
504 Physiological Systems Analysis (3) Application of systems theory, control theory, and analytic modeling strategies to the study of physiological systems. Prerequisites: BIOL 472, MATH 250.
505 Bioengineering Mechanics (3) Passive and active mechanical properties of tissues, rheological materials, models of muscle contraction, pulmonary mechanics, forces in musculoskeletal system.
506 Medical Imaging (3) Medical diagnostic imaging techniques, including generation and detection of ultrasound, X-ray, and nuclear radiation; instrumentation and biological effects. Prerequisite: PHYS 202.
507 Biomedical Signal Processing (3) Data acquisition and digital signal processing focusing on bimedical signal processing issues, including linear phase filters, spectral analysis and wavelets.Prerequisites: BIOE 401, 402, Bioll 041 or 472, Math 250.
508 (MATSE 508) Biomedical Materials (3) Properties and methods of producing metallic, ceramic, and polymeric materials used for biomedical applications. Professor Paul Brown.
510 Biomedical Applications of Microelectromechanical Sytems (BIOMEMS) and Bio Nanotechnology (3) Effective Date: SP2005 Introduction to BioMEMS and Bionanotechnology. Topics include: electromechanical and chemical biosensors, microfluidics microscale separations, and surface patterning for cellular engineering. Prerequisite: E E 418, BIOE 201.
512 Cell and Molecular Bioengineering (3) Graduate level cell and molecular biology course for engineers emphasizing molecular mechanisms.
513 Bioengineering Laboratory Techniques (3) Laboratory techniques in cell molecular biology, protein biochemistry, and cell culture with an emphasis on engineering analysis and quantification. Prerequisites: BIOE 512.
515 Cellular Mechanics and Biophysics (3). Advanced topics and recent developments in cellular engineering; applications of engineering science to cell biology. Prerequisite: BIOE 505.
516 Ultrasonic Imaging (3) Advanced topics and recent developments in ultrasonic imaging will be discussed. Prerequisite: BIOE506 or equivalent.
517 (MATSE 517) Biomedical Materials Surface Science (3) Special properties of surfaces as an important causative and mediating agent in the biological response to materials. Professor Erwin Vogler.
519 Artificial Organ Design (3) Basic techniques and principles of a multidiscipline approach to artificial organs design. Prerequisites: None.
520 Biophotonics (3) Physical and engineering underpinning of different modalities of laser microscopy and spectroscopy in biophisics, biomedical engineering, and life science applications. Prerequisites: BIOE 512.
536 Ultrasonic Tranducer Arrays (3) Theory, design, fabrication and testing of ultrasonic transducer arrays. Prerequisite: BIOE 506 or BIOE 516.
552 (EMCH 552, IE 552)Mechanics of the musculoskeletal System (3) Structure and Biomechanics of bone, cartilage, and skeletal muscle; dynamics and control of musculoskeletal system models. Prerequisite: consent of program. Prerequisite or concurrent: BIOL 472. Professor Pytel and Professor Andris Freivalds.
553 (IE 553) Engineering of Human Work (3) Physics and physiology of humans at work; models of muscle strength; dynamic movements; neural control; physical work capacity; rest allocation. Prerequisite: BIOL 041 or 472. Professor Andris Freivalds.
576 Bioengineering of the Cardiovascular System (3) Experimental and analytical studies of network branching patterns, regional blood flow, rheology and mechanics of blood cells and vessel. Prerequisite: BIOL 472.
580 Bioengineering Internship (3) Supervised experience at the Milton S. Hershey Medical Center, including rotation through services and work on a minor project. Prerequisite: BIOE 402, 3 credits in Bioengineering at the 500 level. Professor Snyder.
590 Bioengineering Colloquium (1) Weekly series of seminars by speakers from outside and within Penn State University on new and developing research areas in bioengineering, and presentations by registered students on their thesis research. All students are required to attend; M.S. degree students must register at least once and Ph.D. students must register at least twice during their thesis research.
596 Individual Studies (1-9) Opportunity for advanced graduate students to study independently in consultation with a faculty advisor.
597 Special Topics (1-9) This designation is assigned to new or developing graduate courses covering specialized areas of interest in bioengineering. Past offerings have focused on topics such as advanced studies of cardiovascular function, advanced topics in artificial organ design and cellular biomechanics.
597A MRI Theory and Method (3) Formal courses given on a topical or special interest subject which may be offered infrequently; several different topics may be taught in one year or term.
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